Dog allergenic protein encompass a wide array of molecules that trigger allergic responses in susceptible individuals. One of the most prominent allergens is Can f 1, which stands for Canis familiaris allergen 1. It belongs to the lipocalin family, characterized by their barrel-shaped structures with a hydrophobic binding pocket. Lipocalins have a remarkable ability to bind and transport small hydrophobic molecules, which, in the context of dog allergens, often includes proteins associated with allergies.